Celplat is a medication used to treat various types of cancer, including testicular cancer, ovarian cancer, and bladder cancer. Here are some key points about the product:
Composition:
Celplat contains Cisplatin, a platinum-based chemotherapy medication that is used to treat various types of cancer.
Indications:
Celplat is indicated for the treatment of:
- Testicular cancer (metastatic)
- Ovarian cancer (metastatic)
- Bladder cancer (metastatic)
Mechanism of Action:
Cisplatin works by:
- Inhibiting the replication of DNA
- Inducing apoptosis (cell death) in cancer cells
- Interfering with the ability of cancer cells to repair DNA damage
Dosage and Administration:
The recommended dosage of Celplat is:
- 50mg/m² administered as an intravenous infusion over 1-2 hours every 3-4 weeks
- The dose may be adjusted based on the patient’s response to treatment and tolerability
Side Effects:
Common side effects of Celplat include:
- Nausea and vomiting
- Diarrhea
- Fatigue
- Hair loss
- Headache
- Muscle weakness
- Dizziness
Serious side effects can include:
- Severe allergic reactions
- Hemolytic anemia
- Thrombocytopenia (low platelet count)
- Pulmonary toxicity
- Cardiac toxicity
- Neurotoxicity
Contraindications:
Celplat is contraindicated in patients with:
- Hypersensitivity to Cisplatin
- Severe kidney impairment
- Pregnancy or breastfeeding
- Active or suspected infections
Precautions:
- Patients with a history of cardiac disease or cardiac dysfunction should be closely monitored while receiving Celplat.
- Patients with a history of kidney disease or kidney impairment should be closely monitored while receiving Celplat.
- Patients with a history of hearing loss or hearing impairment should be closely monitored while receiving Celplat.
Patient Counseling:
- Patients should be counseled on the importance of taking their medication as directed and not missing doses.
- Patients should be instructed to report any signs of nausea, vomiting, or diarrhea.
- Patients should be advised to report any changes in their appetite or weight loss.
Storage and Handling:
- Store at room temperature (20°C to 25°C) and protected from moisture.
- Do not freeze or expose to direct sunlight.
- Use within 24 hours of opening.
Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.
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