Canmab 150mg

Canmab 150 is a medication used to treat certain types of breast cancer, including HER2-positive breast cancer. Here are some key points about the product:

Composition:

Canmab 150 contains Trastuzumab, a humanized monoclonal antibody that targets the HER2 protein.

Indications:

Canmab 150 is indicated for the treatment of:

1. HER2-positive breast cancer
2. Metastatic breast cancer
3. Adjuvant treatment of HER2-positive breast cancer

Mechanism of Action:

Trastuzumab works by:

1. Binding to the HER2 protein on the surface of breast cancer cells
2. Inhibiting the growth and proliferation of these cells
3. Reducing the production of vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF)

Dosage and Administration:

The recommended dosage of Canmab 150 is:

• 150mg administered as an intravenous infusion every 3-4 weeks
• Administered in a healthcare setting under the supervision of a healthcare professional

Side Effects:

Common side effects of Canmab 150 include:

1. Fever
2. Chills
3. Nausea and vomiting
4. Fatigue
5. Headache
6. Increased risk of infections
7. Rash

Serious side effects can include:

1. Cardiac toxicity (e.g., heart failure, decreased cardiac function)
2. Severe allergic reactions
3. Hypersensitivity reactions (e.g., anaphylaxis)
4. Hemolytic uremic syndrome (HUS)

Contraindications:

Canmab 150 is contraindicated in patients with:

1. Hypersensitivity to Trastuzumab
2. Pregnancy or breastfeeding
3. Cardiac disease or cardiac dysfunction

Precautions:

1. Patients with a history of cardiac disease or cardiac dysfunction should be closely monitored while receiving Canmab 150.
2. Patients with a history of liver disease or liver impairment should be closely monitored while receiving Canmab 150.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of fever, chills, or nausea.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from moisture.
• Do not freeze or expose to direct sunlight.
• Use within 24 hours of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.