Tauritmo is a prescription medication used to treat a type of cancer called systemic mastocytosis (SM). SM is a rare blood disorder that occurs when the body produces too many mast cells, which can cause a range of symptoms including anaphylaxis, diarrhea, and bone pain.
Composition:
- Tauritmo: Midostaurin 25mg Capsules
Mechanism of Action:
Midostaurin, the active ingredient in Tauritmo, works by:
- Inhibiting the activity of protein kinases, which are enzymes that play a key role in the development and growth of cancer cells.
- Reducing the production of mast cells, which can help alleviate symptoms associated with SM.
Indications:
Tauritmo is approved for the treatment of:
- Systemic mastocytosis (SM) in patients who have a platelet count of 100,000 per microliter or higher.
- SM in patients who have a KIT mutation (a type of genetic mutation that is associated with SM).
Dosage:
The recommended dosage of Tauritmo is:
- 25mg orally, twice daily.
- The recommended duration of treatment is until disease progression or unacceptable toxicity.
Side Effects:
Common side effects of Tauritmo include:
- Nausea
- Vomiting
- Diarrhea
- Fatigue
- Headache
- Dizziness
- Increased risk of bleeding
- Increased risk of infections
- Increased risk of liver damage
Recommendation:
Tauritmo is recommended for patients with systemic mastocytosis who have a platelet count of 100,000 per microliter or higher and have a KIT mutation.
Important Note:
- Patients taking Tauritmo should be closely monitored for signs of liver damage or kidney damage.
- Patients taking Tauritmo should avoid taking medications that may interact with it, such as anticoagulants or medications that can increase the risk of bleeding.
- Pregnant or breastfeeding women should not use Tauritmo, as it may harm the fetus or infant.
- Regular follow-up appointments with your healthcare provider are necessary to monitor the effectiveness of Tauritmo and to detect any potential side effects or complications.
Special Precautions:
- Patients with a history of liver disease or kidney disease should be closely monitored while taking Tauritmo.
- Patients taking Tauritmo should avoid taking medications that may increase the risk of liver damage or kidney damage.
- Patients with a history of bleeding disorders or platelet disorders should be closely monitored while taking Tauritmo.
Contraindications:
- Patients with severe liver disease or severe kidney disease should not use Tauritmo.
- Patients who are pregnant or breastfeeding should not use Tauritmo.
- Patients who are allergic to midostaurin or any other component of Tauritmo should not use it.
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