Luprodex 3.75

Luprodex 3.75 is a medication used to treat certain conditions related to hormone imbalances, including prostate cancer and endometriosis. Here are some key points about the product:

Composition:

Luprodex 3.75 contains Leuprolide, a synthetic gonadotropin-releasing hormone (GnRH) analog that acts as an agonist.

Indications:

Luprodex 3.75 is indicated for the treatment of:

1. Advanced prostate cancer
2. Symptomatic endometriosis
3. Uterine leiomyomata (fibroids)

Mechanism of Action:

Leuprolide works by:

1. Binding to GnRH receptors in the pituitary gland, leading to a decrease in the production of gonadotropins (luteinizing hormone and follicle-stimulating hormone)
2. Reducing the production of sex hormones (estrogen and testosterone) in the body
3. Inhibiting the growth and progression of cancer cells

Dosage and Administration:

The recommended dosage of Luprodex 3.75 is:

• 3.75mg administered as an intramuscular injection every 3 months
• Administered in a healthcare setting under the supervision of a healthcare professional

Side Effects:

Common side effects of Luprodex 3.75 include:

1. Hot flashes
2. Depression
3. Anxiety
4. Nausea and vomiting
5. Headache
6. Fatigue
7. Increased risk of infections

Serious side effects can include:

1. Allergic reactions
2. Cardiovascular events (e.g., heart attack, stroke)
3. Hypersensitivity reactions
4. Increased risk of fractures

Contraindications:

Luprodex 3.75 is contraindicated in patients with:

1. Hypersensitivity to Leuprolide
2. Pregnancy or breastfeeding
3. Known or suspected pregnancy or lactation

Precautions:

1. Patients with a history of cardiovascular disease or stroke should be closely monitored while receiving Luprodex 3.75.
2. Patients with a history of bone disorders or osteoporosis should be closely monitored while receiving Luprodex 3.75.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of hot flashes, depression, or anxiety.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from moisture.
• Do not freeze or expose to direct sunlight.
• Use within 24 hours of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.