Krabeva 100mg

Krabeva 100 is a medication used to treat certain types of cancer, including colon, breast, and lung cancer. Here are some key points about the product:

Composition:

Krabeva 100 contains Bevacizumab, a recombinant humanized monoclonal antibody that inhibits the activity of vascular endothelial growth factor (VEGF).

Indications:

Krabeva 100 is indicated for the treatment of:

1. Metastatic colorectal cancer
2. Metastatic breast cancer
3. Non-small cell lung cancer
4. Recurrent glioblastoma
5. Ovarian cancer

Mechanism of Action:

Bevacizumab works by:

1. Inhibiting the activity of VEGF, which is a key growth factor for tumor blood vessels
2. Reducing the formation of new blood vessels in tumors
3. Inhibiting the growth and progression of cancer cells

Dosage and Administration:

The recommended dosage of Krabeva 100 is:

• 100mg administered as an intravenous infusion every 2-3 weeks
• Administered in a healthcare setting under the supervision of a healthcare professional

Side Effects:

Common side effects of Krabeva 100 include:

1. Hypertension
2. Headache
3. Fatigue
4. Nausea and vomiting
5. Diarrhea
6. Rash
7. Increased risk of infections

Serious side effects can include:

1. Hypersensitivity reactions (e.g., anaphylaxis)
2. Gastrointestinal perforation
3. Hemorrhage
4. Increased risk of arterial thromboembolic events (e.g., heart attack, stroke)
5. Severe allergic reactions

Contraindications:

Krabeva 100 is contraindicated in patients with:

1. Hypersensitivity to Bevacizumab
2. Pregnancy or breastfeeding
3. Active bleeding or a history of gastrointestinal perforation

Precautions:

1. Patients with a history of hypertension should be closely monitored while receiving Krabeva 100.
2. Patients with a history of cardiac disease or stroke should be closely monitored while receiving Krabeva 100.
3. Patients with a history of liver disease or liver impairment should be closely monitored while receiving Krabeva 100.

Patient Counseling:

• Patients should be counseled on the importance of taking their medication as directed and not missing doses.
• Patients should be instructed to report any signs of hypertension, headache, or fatigue.
• Patients should be advised to report any changes in their appetite or weight loss.

Storage and Handling:

• Store at room temperature (20°C to 25°C) and protected from moisture.
• Do not freeze or expose to direct sunlight.
• Use within 24 hours of opening.

Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.