(Bdparp Olaparib) 150mg Tablet is a medication used to treat certain types of cancer. Here are some key points about the product:
Composition:
Bdparp(Olaparib) 150mg Tablet contains olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor that targets cancer cells.
Indications:
Bdparp(Olaparib) 150mg Tablet is indicated for the treatment of:
- BRCA-mutated advanced ovarian cancer in patients who have received at least three previous chemotherapy regimens
- BRCA-mutated metastatic breast cancer in patients who have received at least two previous chemotherapy regimens
Mechanism of Action:
Bdparp Olaparib 150mg Tablet works by:
- Inhibiting the activity of PARP, an enzyme that helps repair DNA damage
- Targeting cancer cells that have BRCA mutations, which impair their ability to repair DNA damage
- Reducing the growth and proliferation of cancer cells
Dosage and Administration:
The recommended dosage of Bdparp (Olaparib) 150mg Tablet is:
- 150mg taken orally twice daily, with or without food
- Take at the same time each day
Side Effects:
Common side effects of Bdparp (Olaparib) 150mg Tablet include:
- Fatigue
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Rash
Serious side effects can include:
- Myelodysplastic syndrome (MDS)
- Acute myeloid leukemia (AML)
- Hepatotoxicity (e.g., liver damage)
- Hematological toxicity (e.g., anemia, thrombocytopenia)
Contraindications:
Bdparp(Olaparib) 150mg Tablet is contraindicated in patients with:
- Hypersensitivity to olaparib
- Pregnancy or breastfeeding
- Severe hepatic impairment (Child-Pugh C)
Precautions:
- Patients with a history of liver disease or liver damage should be closely monitored while receiving Bdparp (Olaparib) 150mg Tablet.
- Patients with a history of hematological disorders or blood dyscrasias should be closely monitored while receiving Bdparp (Olaparib) 150mg Tablet.
Patient Counseling:
- Patients should be counseled on the importance of taking their medication as directed and not missing doses.
- Patients should be instructed to report any signs of fatigue, nausea, or abdominal pain.
- Patients should be advised to report any changes in their menstrual cycle or symptoms of bone loss.
Storage and Handling:
- Store bottles at room temperature between 15°C and 30°C (59°F and 86°F).
- Do not expose to direct sunlight or moisture.
- Use within 24 hours of opening.
Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.
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