Arimidex (Anastrozole) 1mg Tablets is a medication used to treat breast cancer in women. Here are some key points about the product:
Composition:
Arimidex 1mg Tablets contains anastrozole, a non-steroidal aromatase inhibitor that reduces the production of estrogen in the body.
Indications:
Arimidex 1mg Tablets is indicated for the treatment of:
- Hormone-receptor-positive breast cancer in postmenopausal women
- Adjuvant treatment of hormone-receptor-positive breast cancer in postmenopausal women
- Advanced breast cancer in postmenopausal women who have received prior therapy
Mechanism of Action:
Anastrozole 1mg Tablets works by:
- Inhibiting the activity of aromatase, an enzyme that converts androgens into estrogens
- Reducing the production of estrogen, which can stimulate the growth of breast cancer cells
Dosage and Administration:
The recommended dosage of Arimidex 1mg Tablets is:
- 1mg taken orally once daily, with or without food
- Take at the same time each day
Side Effects:
Common side effects of Arimidex 1mg Tablets include:
- Hot flashes
- Fatigue
- Headache
- Dizziness
- Nausea
- Vomiting
- Abdominal pain
Serious side effects can include:
- Liver damage
- Bone fractures
- Cardiovascular disease
- Hematological toxicity (e.g., anemia, neutropenia)
Contraindications:
Arimidex 1mg Tablets is contraindicated in patients with:
- Hypersensitivity to anastrozole
- Pregnancy or breastfeeding
- Severe hepatic impairment (Child-Pugh C)
Precautions:
- Patients with a history of liver disease or liver damage should be closely monitored while receiving Arimidex 1mg Tablets.
- Patients with a history of cardiovascular disease or cardiovascular risk factors should be closely monitored while receiving Arimidex 1mg Tablets.
Patient Counseling:
- Patients should be counseled on the importance of taking their medication as directed and not missing doses.
- Patients should be instructed to report any signs of hot flashes, fatigue, or abdominal pain.
- Patients should be advised to report any changes in their menstrual cycle or symptoms of bone loss.
Storage and Handling:
- Store bottles at room temperature between 15°C and 30°C (59°F and 86°F).
- Do not expose to direct sunlight or moisture.
- Use within 24 hours of opening.
Please note that the dosage and administration information is based on the recommended dosage and may vary depending on individual patient needs and circumstances.
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