Herceptin 440 is a prescription medication used to treat certain types of breast cancer and stomach cancer. It is a monoclonal antibody that targets the HER2 protein, which is found on the surface of some cancer cells.
Composition:
- Herceptin 440: Trastuzumab (440mg)
Mechanism of Action:
Herceptin 440 works by:
- Binding to the HER2 protein on the surface of cancer cells, which can help to:
- Prevent the growth and spread of cancer cells
- Reduce the production of certain growth factors that can promote cancer growth
- Enhance the effects of chemotherapy
Indications:
Herceptin 440 is approved for the treatment of:
- Metastatic breast cancer in women who have HER2-positive tumors
- Adjuvant breast cancer in women who have HER2-positive tumors and have undergone surgery
- Gastric cancer in patients with HER2-positive tumors
Dosage:
The recommended dosage of Herceptin 440 is:
- 440mg as an infusion over 90 minutes every 3 weeks
- The recommended duration of treatment is until disease progression or unacceptable toxicity occurs
Side Effects:
Common side effects of Herceptin 440 include:
- Infusion reactions
- Fatigue
- Headache
- Muscle pain
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Fever
- Chills
Recommendation:
Herceptin 440 is recommended for patients with HER2-positive breast cancer or gastric cancer who have not responded to other treatments.
Important Note:
- Patients taking Herceptin 440 should be closely monitored for signs of cardiac problems, such as heart failure or arrhythmias.
- Patients taking Herceptin 440 should avoid taking medications that may interact with it, such as anticoagulants or medications that can increase the risk of bleeding.
- Pregnant or breastfeeding women should not use Herceptin 440, as it may harm the fetus or infant.
- Regular follow-up appointments with your healthcare provider are necessary to monitor the effectiveness of Herceptin 440 and to detect any potential side effects or complications.
Special Precautions:
- Patients with a history of heart problems or liver disease should be closely monitored while taking Herceptin 440.
- Patients with a history of severe allergic reactions should be closely monitored while taking Herceptin 440.
Contraindications:
- Patients who are allergic to trastuzumab or any other component of Herceptin 440 should not use it.
- Patients who are pregnant or breastfeeding should not use Herceptin 440.
- Patients with severe liver disease or severe kidney disease should not use Herceptin 440.
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