Suninat 12.5mg

Suninat 12.5 is a prescription medication used to treat certain types of cancer, including gastrointestinal stromal tumors (GIST), advanced renal cell carcinoma (RCC), and pancreatic neuroendocrine tumors (pNET). It is a tyrosine kinase inhibitor that works by blocking the growth of cancer cells.

Composition:

• Suninat 12.5: Sunitinib 12.5mg

Mechanism of Action:

Sunitinib, the active ingredient in Suninat, is a tyrosine kinase inhibitor that works by:

1. Blocking the growth of cancer cells by inhibiting the action of specific enzymes that promote cell growth and division.
2. Inhibiting the formation of new blood vessels that feed the tumor, which helps to reduce its growth and spread.

Indications:

Suninat is approved for the treatment of:

1. Gastrointestinal stromal tumors (GIST) that have progressed or recurred after treatment with other medications.
2. Advanced renal cell carcinoma (RCC) that has progressed after treatment with other medications.
3. Pancreatic neuroendocrine tumors (pNET) that have progressed or recurred after treatment with other medications.

Dosage:

The recommended dosage of Suninat is:

• 12.5mg orally once daily, taken at the same time every day.
• The recommended duration of treatment is until disease progression or unacceptable toxicity.

Side Effects:

Common side effects of Suninat include:

1. Fatigue
2. Diarrhea
3. Nausea
4. Vomiting
5. Abdominal pain
6. Constipation
7. Increased risk of bleeding or bruising
8. Skin rash
9. Hair loss
10. High blood pressure

Recommendation:

Suninat is recommended for patients who have been diagnosed with GIST, RCC, or pNET and have not responded to other treatments or have disease that has progressed after surgery and radiation therapy.

Important Note:

• Patients taking Suninat should be closely monitored for signs of bleeding or bruising due to the risk of thrombocytopenia.
• Patients taking Suninat should avoid taking medications that may increase the risk of bleeding or bruising.
• Pregnant or breastfeeding women should not use Suninat, as it may harm the fetus or infant.
• Regular follow-up appointments with your healthcare provider are necessary to monitor the effectiveness of Suninat and to detect any potential side effects or complications.

Special Precautions:

• Patients with a history of kidney disease should be closely monitored for signs of worsening kidney function while taking Suninat.
• Patients taking Suninat should avoid taking medications that may interact with it, such as anticoagulants or medications that can increase blood pressure.
• Patients with a history of heart disease or high blood pressure should be closely monitored while taking Suninat.