MODVATE: Combination of Beclomethasone + Clotrimazole + Neomycin
Composition:
- Beclomethasone: A corticosteroid that reduces inflammation and immune response.
- Clotrimazole: An antifungal agent that inhibits the growth of fungi.
- Neomycin: An aminoglycoside antibiotic that helps to prevent bacterial infections.
Mechanism of Action:
MODVATE utilizes a multi-pronged approach:
- Beclomethasone works by inhibiting the release of substances in the body that cause inflammation, thus alleviating symptoms of inflammatory conditions.
- Clotrimazole interferes with the integrity of the fungal cell membrane, causing cell death and effectively treating fungal infections.
- Neomycin binds to bacterial ribosomes, inhibiting protein synthesis which leads to bacteria’s ultimate death.
Dosage:
- The dosage may vary based on the specific condition being treated.
- It is important to follow the healthcare provider’s instructions regarding the exact dosage and duration of treatment.
- Typically applied as a topical formulation (cream, ointment) 2-3 times daily.
Usage:
- MODVATE is used for the treatment of skin conditions involving inflammation, bacterial infection, and fungal infection such as:
- Dermatitis
- Eczema
- Certain types of fungal infections
- It is applied to the affected area of the skin.
Side Effects:
Possible side effects include:
- Local irritation (burning, itching, redness)
- Allergic reactions (rash, hives)
- Prolonged use may lead to skin thinning or systemic absorption of corticosteroids.
- Risk of developing resistance to neomycin if used improperly.
Recommendations:
- Wash hands thoroughly before and after applying the product.
- Apply a thin layer to the affected area without occluding the site unless directed.
- Avoid applying to broken or open skin unless advised by a healthcare provider.
- If side effects occur, or if the condition does not improve within a few days, consult a healthcare professional.
Important Note:
- Use this medication only for the conditions prescribed by your healthcare provider.
- Prolonged use or overuse can lead to complications, including secondary infections or systemic effects from corticosteroids.
- Avoid contact with eyes. If contact occurs, rinse immediately with plenty of water.
Always consult a healthcare provider for personalized medical advice and information regarding this medication.
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