Tenovate GN Cream

Tenovate GN Cream

Composition:

• Betamethasone (0.1% w/w) – A potent corticosteroid that helps reduce inflammation, redness, and itching.
• Gentamicin (0.1% w/w) – An antibiotic that kills or inhibits the growth of bacteria, helping to treat infections.
• Miconazole (2% w/w) – An antifungal that is effective against a range of fungal infections by inhibiting fungal cell membrane synthesis.

Mechanism of Action:

• Betamethasone: Works by inhibiting the release of inflammatory mediators, decreasing the inflammatory response, and suppressing the immune system’s response that contributes to inflammation and itching.
• Gentamicin: Binds to bacterial ribosomes, inhibiting protein synthesis, which is essential for bacterial growth and replication. Effective against certain gram-negative and some gram-positive bacteria.
• Miconazole: Disrupts the synthesis of ergosterol, an essential component of fungal cell membranes, leading to increased permeability and cell death.

Dosage:

• Apply a thin layer of Tenovate GN Cream to the affected area 1-2 times daily, or as directed by a healthcare professional.
• Ensure to wash hands before and after applying the cream unless treating the hands.

Usage:

• Used for the treatment of inflammatory skin conditions complicated by bacterial and/or fungal infections, such as:
  • Dermatitis
  • Eczema
  • Psoriasis with secondary infections
  • Impetigo

Side Effects: Potential side effects may include:

• Skin irritation, burning, or stinging at the application site
• Dryness of the skin
• Folliculitis (inflammation of hair follicles)
• Allergic reactions (rash, itching)
• Prolonged use may lead to skin atrophy or systemic absorption causing adrenal suppression if used over large areas or under occlusive dressings.

Recommendations:

• Use for the prescribed duration to minimize the risk of side effects.
• Avoid applying to large areas of the body, on broken skin, or under bandages unless directed by a healthcare professional.
• Do not use on the face, groin, or axilla unless specifically directed.
• If no improvement is seen after 2 weeks of treatment, consult a healthcare provider.
• Inform your healthcare provider about all medications you are taking to avoid drug interactions.

Important Note:

• Tenovate GN Cream is for external use only and should not be ingested.
• Do not use the cream if you are allergic to any of its components.
• Keep out of the reach of children and store it at room temperature.
• Consult with a healthcare provider if you are pregnant, breastfeeding, or have any underlying health conditions before using this medication.