Hepcvel Cap

### Hepcvel Capsule **PRODUCT DESCRIPTION:** Hepcvel is a fixed-dose combination antiviral medication that contains Ledipasvir and Sofosbuvir. It is used for the treatment of chronic hepatitis C virus (HCV) infection. **ACTIVE INGREDIENTS:** – **Ledipasvir (90 mg)**: An NS5A inhibitor that prevents the replication of the Hepatitis C virus by inhibiting the viral protein necessary for the virus’s replication and assembly. – **Sofosbuvir (400 mg)**: An NS5B polymerase inhibitor that interferes with viral RNA synthesis, effectively stopping the virus from replicating within the host’s liver cells. **INDICATIONS:** Hepcvel is indicated for: – The treatment of chronic hepatitis C virus (HCV) infection in adults and in children aged 12 years and older (weighing at least 35 kg). – It is effective against several HCV genotypes, commonly including genotypes 1, 4, 5, and 6. **DOSAGE AND ADMINISTRATION:** – **Dosage**: The usual dosage is one capsule taken orally once daily, with or without food. – **Treatment Duration**: Treatment typically lasts from 8 to 24 weeks, depending on various factors such as: – HCV genotype – Previous treatment history – Presence of liver cirrhosis or other comorbidities **SIDE EFFECTS:** Hepcvel is generally well tolerated. Common side effects can include: – Fatigue – Headache – Nausea – Diarrhea – Insomnia – Anemia (more common if prescribed with ribavirin) Serious side effects are rare but may include: – Liver complications – Allergic reactions **CONTRAINDICATIONS:** – Hepcvel is contraindicated in individuals with a known hypersensitivity to either Ledipasvir or Sofosbuvir, or to any components of the formulation. – It is not recommended for use in patients with decompensated liver disease (Child-Pugh Class B or C). **IMPORTANT NOTES:** – **Drug Interactions**: Hepcvel may interact with other medications, particularly those that affect liver enzymes. It is critical to inform healthcare providers about all other medications being taken, including over-the-counter drugs and supplements. – **Monitoring**: Regular monitoring of liver function and hematological parameters may be required during treatment. – **Adherence to Therapy**: Strict adherence to the prescribed dosing regimen is important for successful treatment outcomes. ### Summary: Hepcvel combines Ledipasvir and Sofosbuvir for the management of chronic hepatitis C virus infection. It is important for patients to follow the prescribed treatment plan and maintain open communication with healthcare providers regarding any side effects, medication interactions, or health issues during treatment. Always consult with a healthcare professional for personalized medical advice tailored to individual health needs.