Prolavir LR Tablet

Prolavir LR Tablet is a combination medication that contains Lopinavir and Ritonavir, which is commonly used in the treatment of HIV-1 infection. This combination is especially effective in the management of HIV due to its antiviral properties.

Key Components:

1. Lopinavir:
   • Class: Protease Inhibitor (PI)
   • Mechanism of Action: Lopinavir works by inhibiting the protease enzyme that the HIV virus needs to replicate. By preventing this enzyme from functioning, Lopinavir stops the virus from maturing and replicating.
2. Ritonavir:
   • Class: Protease Inhibitor (PI)
   • Mechanism of Action: Ritonavir also inhibits the protease enzyme, but it is primarily included in this combination to boost the effectiveness of Lopinavir. Ritonavir inhibits the metabolism of Lopinavir in the liver, allowing higher concentrations of Lopinavir to remain in the body for a longer duration.

Uses:

• HIV Treatment: Prolavir LR is used as part of a comprehensive antiretroviral therapy (ART) regimen for the treatment of HIV-1 infection. The combination therapy helps in suppressing the viral load and improving immune function.

Dosage and Administration:

• Dosage: The specific dosage of Prolavir LR should be determined by a healthcare provider based on the individual patient’s needs, age, weight, and other factors. It is commonly prescribed as one tablet taken twice daily with food to enhance absorption.
• Administration: It is important to take Prolavir LR with food for better absorption and to minimize gastrointestinal side effects.

Side Effects:

Common side effects may include:

• Nausea
• Diarrhea
• Vomiting
• Abdominal pain
• Fatigue
• Headache
• Increased cholesterol or triglyceride levels

Serious side effects can include:

• Liver Dysfunction: Liver enzymes should be monitored, particularly in patients with pre-existing liver disease.
• Pancreatitis: There is a risk of developing pancreatitis, especially at higher doses.

Recommendations:

• Regular Monitoring: Patients should have regular follow-ups to monitor liver function and lipid levels, as Ritonavir can increase cholesterol and triglyceride levels.
• Adherence: It is crucial to adhere strictly to the prescribed treatment regimen to ensure viral suppression and minimize the risk of developing drug resistance.

As always, consult your healthcare provider for more detailed information regarding Prolavir LR Tablet, including individual dosing, potential drug interactions, and the management of side effects.