Palbace 100mg

Palbace 100mg is a prescription medication used to treat certain types of breast cancer, including hormone receptor-positive and human epidermal growth factor receptor 2 (HER2)-negative breast cancer. It is a cyclin-dependent kinase (CDK) inhibitor that works by blocking the activity of CDK4 and CDK6, which are key players in the growth and spread of cancer cells.

Composition:

• Palbociclib 100mg

Mechanism of Action:

Palbociclib works by:

1. Inhibiting the activity of CDK4 and CDK6, which are key players in the growth and spread of cancer cells
2. Blocking the signaling pathways that promote cancer cell growth and survival
3. Reducing the production of proteins that contribute to cancer cell growth and survival

Indications:

Palbace 100mg is approved for the treatment of:

• Hormone receptor-positive and HER2-negative breast cancer in combination with letrozole or fulvestrant
• Hormone receptor-positive and HER2-negative breast cancer in combination with endocrine therapy

Dosage:

The recommended dosage of Palbace 100mg is:

• 100mg administered orally once daily for at least 21 days in a 28-day cycle
• The recommended duration of treatment is until disease progression or unacceptable toxicity occurs

Side Effects:

Common side effects of Palbace 100mg include:

1. Fatigue
2. Nausea and vomiting
3. Diarrhea
4. Abdominal pain
5. Headache
6. Dizziness
7. Increased risk of infections
8. Increased risk of bleeding
9. Increased risk of neutropenia (low white blood cell count)
10. Increased risk of thrombocytopenia (low platelet count)

Recommendation:

Palbace 100mg is recommended for patients with hormone receptor-positive and HER2-negative breast cancer who have not responded to other treatments or who have progressed on or are intolerant to other endocrine therapies.

Important Note:

• Patients taking Palbace 100mg should be closely monitored for signs of neutropenia or thrombocytopenia.
• Patients taking Palbace 100mg should avoid taking medications that may interact with it, such as warfarin or phenytoin.
• Pregnant or breastfeeding women should not use Palbace 100mg, as it may harm the fetus or infant.
• Regular follow-up appointments with your healthcare provider are necessary to monitor the effectiveness of Palbace 100mg and to detect any potential side effects or complications.

Special Precautions:

• Patients with a history of neutropenia or thrombocytopenia should be closely monitored while taking Palbace 100mg.
• Patients with a history of bleeding disorders should be closely monitored while taking Palbace 100mg.

Contraindications:

• Patients who are allergic to palbociclib or any other component of Palbace 100mg should not use it.
• Patients who are pregnant or breastfeeding should not use Palbace 100mg.
• Patients with severe neutropenia or thrombocytopenia should not use Palbace 100mg.

Warnings:

• Palbace 100mg can cause severe neutropenia or thrombocytopenia, especially in patients with a history of these conditions.
• Patients with a history of neutropenia or thrombocytopenia should be closely monitored while taking Palbace 100mg.
• Patients should report any changes in their blood cell count or symptoms of infection to their healthcare provider immediately.