CANESTEN V CREAM is a topical antifungal cream containing Clotrimazole, specifically formulated for the treatment of vaginal yeast infections (vulvovaginal candidiasis). It provides localized relief from itching, burning, and discharge associated with fungal infections.
Composition
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Active Ingredient:
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Clotrimazole (2% w/w – 10 mg per 1g of cream).
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Base:Â Aqueous, hypoallergenic cream.
Mechanism of Action
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Fungicidal & Fungistatic:
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Disrupts ergosterol synthesis in fungal cell membranes.
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Causes cell membrane damage, leading to fungal cell death.
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Effective Against:
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Candida albicans (most common yeast infection cause).
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Other Candida species and some dermatophytes.
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Dosage & Administration
For Vaginal Yeast Infections:
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Apply externally (vulvar area):
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Use 2–3 times daily for 7–14 days (or as prescribed).
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Intravaginal application (if needed):
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Use with the provided applicator (insert 1 full applicator at bedtime for 3–7 days).
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How to Use:
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Wash hands before and after application.
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Apply a thin layer to the external genital area (vulva) to relieve itching.
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For internal use, fill the applicator and insert into the vagina at bedtime.
Uses (Indications)
✔ Vulvovaginal candidiasis (yeast infection).
✔ External itching, redness, and discomfort.
✔ Adjuvant therapy with oral antifungals (if needed).
Storage
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Store at room temperature (below 30°C).
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Keep the tube tightly closed.
Recommendations
✔ Complete the full course even if symptoms improve early.
✔ Avoid tampons, douches, or sexual intercourse during treatment.
✔ Wear cotton underwear to reduce moisture buildup.
✔ Partner treatment is usually unnecessary unless symptomatic.
Important Note
Contraindications:
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Hypersensitivity to clotrimazole or imidazole antifungals.
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Open wounds or broken skin near the application area.
Side Effects:
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Mild:Â Local burning, irritation, or redness.
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Rare:Â Allergic reactions (rash, swelling).
Drug Interactions:
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No significant systemic interactions (minimal absorption).
Pregnancy & Lactation:
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Safe in 2nd & 3rd trimesters (Category B).
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Breastfeeding: Low absorption (safe for nursing mother).
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