DUPHASTON 10 MG

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  • Brand Name: Duphaston

  • Generic Name: Dydrogesterone

  • Therapeutic Class: Retroprogesterone (Synthetic Progestogen)

  • Form: 10 mg film-coated tablets

  • Key Feature:

    • No androgenic/estrogenic/glucocorticoid activity

    • Does not inhibit ovulation


2. COMPOSITION

Component Role
Dydrogesterone Active ingredient (structurally similar to natural progesterone)
Lactose monohydrate Filler
Hypromellose Coating agent
Magnesium stearate Lubricant

(Gluten-free formulation)


3. MECHANISM OF ACTION

✔ Binds selectively to progesterone receptors ✔ Produces secretory endometrium → supports implantation ✔ Maintains pregnancy by preventing uterine contractions ✔ No thermogenic effect (basal body temperature unchanged)


4. DOSAGE & ADMINISTRATION

By Indication

Condition Dosage Regimen Duration
Endometriosis 10 mg 2-3x daily Days 5-25 of cycle
Dysmenorrhea 10 mg 2x daily Days 5-25 of cycle
Threatened Miscarriage 40 mg stat → 10 mg every 8h Until symptoms resolve +1 week
Luteal Phase Support 10 mg 2x daily From ovulation → 10-12 weeks gestation
HRT Combination 10 mg daily Last 12-14 days of estrogen cycle

Key Notes:

  • Take with food to reduce nausea

  • No need for dose tapering before discontinuation


5. INDICATIONS

✅ Menstrual disorders (dysmenorrhea, irregular cycles) ✅ Endometriosis ✅ Luteal phase defect (fertility treatments) ✅ Threatened/recurrent miscarriage ✅ HRT adjunct (endometrial protection)


6. STORAGE CONDITIONS

  • Temperature: Below 30°C

  • Humidity: Keep in original blister pack

  • Shelf Life: 3 years


7. KEY RECOMMENDATIONS

✔ For fertility patients:

  • Start after confirmed ovulation (avoid anovulatory cycles)

  • Combine with ultrasound monitoring

✔ For HRT:

  • Ensure adequate estrogen priming first

  • Withdraw bleeding expected after progestin phase

✔ Safety advantage:

  • No negative impact on lipids/carbohydrate metabolism


8. IMPORTANT SAFETY NOTES

Contraindications

❌ Severe hepatic impairment ❌ Known progesterone-sensitive tumors ❌ Undiagnosed vaginal bleeding

Adverse Effects

Common (≥1%) Rare (<0.1%)
Breakthrough bleeding Allergic reactions
Mild nausea Thrombotic events (very rare)
Breast tenderness

Pregnancy/Lactation

  • Pregnancy (Category not assigned): Safe for luteal support

  • Breastfeeding: Minimal milk transfer


9. COMPARISON WITH OTHER PROGESTINS

Parameter Dydrogesterone Medroxyprogesterone Micronized Progesterone
Androgenic Effects None Mild None
Sedation No No Yes
Fertility-Friendly Yes No Yes
Metabolic Impact Neutral Negative Neutral

10. PATIENT COUNSELING

✔ Take consistently at same times daily ✔ Report:

  • Heavy/prolonged bleeding

  • Severe abdominal pain

  • Visual disturbances (rare migraine precursor) ✔ Fertility patients:

  • Continue until placenta forms (∼10-12 weeks)

  • No abrupt discontinuation needed


CONCLUSION

Duphaston 10 mg offers targeted progesterone effects without androgenic/ metabolic side effects, making it ideal for:

  • Fertility support (no ovulation suppression)

  • Long-term endometrial protection in HRT

  • High-risk pregnancy management

  • Brand Name: Duphaston

  • Generic Name: Dydrogesterone

  • Therapeutic Class: Retroprogesterone (Synthetic Progestogen)

  • Form: 10 mg film-coated tablets

  • Key Feature:

    • No androgenic/estrogenic/glucocorticoid activity

    • Does not inhibit ovulation


2. COMPOSITION

Component Role
Dydrogesterone Active ingredient (structurally similar to natural progesterone)
Lactose monohydrate Filler
Hypromellose Coating agent
Magnesium stearate Lubricant

(Gluten-free formulation)


3. MECHANISM OF ACTION

✔ Binds selectively to progesterone receptors
✔ Produces secretory endometrium → supports implantation
✔ Maintains pregnancy by preventing uterine contractions
✔ No thermogenic effect (basal body temperature unchanged)


4. DOSAGE & ADMINISTRATION

By Indication

Condition Dosage Regimen Duration
Endometriosis 10 mg 2-3x daily Days 5-25 of cycle
Dysmenorrhea 10 mg 2x daily Days 5-25 of cycle
Threatened Miscarriage 40 mg stat → 10 mg every 8h Until symptoms resolve +1 week
Luteal Phase Support 10 mg 2x daily From ovulation → 10-12 weeks gestation
HRT Combination 10 mg daily Last 12-14 days of estrogen cycle

Key Notes:

  • Take with food to reduce nausea

  • No need for dose tapering before discontinuation


5. INDICATIONS

✅ Menstrual disorders (dysmenorrhea, irregular cycles)
✅ Endometriosis
✅ Luteal phase defect (fertility treatments)
✅ Threatened/recurrent miscarriage
✅ HRT adjunct (endometrial protection)


6. STORAGE CONDITIONS

  • Temperature: Below 30°C

  • Humidity: Keep in original blister pack

  • Shelf Life: 3 years


7. KEY RECOMMENDATIONS

✔ For fertility patients:

  • Start after confirmed ovulation (avoid anovulatory cycles)

  • Combine with ultrasound monitoring

✔ For HRT:

  • Ensure adequate estrogen priming first

  • Withdraw bleeding expected after progestin phase

✔ Safety advantage:

  • No negative impact on lipids/carbohydrate metabolism


8. IMPORTANT SAFETY NOTES

Contraindications

❌ Severe hepatic impairment
❌ Known progesterone-sensitive tumors
❌ Undiagnosed vaginal bleeding

Adverse Effects

Common (≥1%) Rare (<0.1%)
Breakthrough bleeding Allergic reactions
Mild nausea Thrombotic events (very rare)
Breast tenderness

Pregnancy/Lactation

  • Pregnancy (Category not assigned): Safe for luteal support

  • Breastfeeding: Minimal milk transfer


9. COMPARISON WITH OTHER PROGESTINS

Parameter Dydrogesterone Medroxyprogesterone Micronized Progesterone
Androgenic Effects None Mild None
Sedation No No Yes
Fertility-Friendly Yes No Yes
Metabolic Impact Neutral Negative Neutral

10. PATIENT COUNSELING

✔ Take consistently at same times daily
✔ Report:

  • Heavy/prolonged bleeding

  • Severe abdominal pain

  • Visual disturbances (rare migraine precursor)
    ✔ Fertility patients:

  • Continue until placenta forms (∼10-12 weeks)

  • No abrupt discontinuation needed


CONCLUSION

Duphaston 10 mg offers targeted progesterone effects without androgenic/ metabolic side effects, making it ideal for:

  • Fertility support (no ovulation suppression)

  • Long-term endometrial protection in HRT

  • High-risk pregnancy management

We offer a variety of shipping options, including Express Mail Service (EMS), USPS, DHL, FedEx, TNT, UPS, Aramex, Air Cargo, and sea freight.

Terms and Conditions – 

Bulk Orders: You are responsible for any local import duties and taxes in your country.

For Patients: When ordering prescription medicines for personal use, or for a friend or relative, a valid medical practitioner’s script or prescription is required.

Return and Refund Policy: Due to the nature of our products, we cannot accept returns or exchanges once a purchase is made. However, in the event of non-delivery, you are eligible for either a 100% refund or a reshipment of your order.

  • Brand Name: Duphaston

  • Generic Name: Dydrogesterone

  • Therapeutic Class: Retroprogesterone (Synthetic Progestogen)

  • Form: 10 mg film-coated tablets

  • Key Feature:

    • No androgenic/estrogenic/glucocorticoid activity

    • Does not inhibit ovulation


2. COMPOSITION

Component Role
Dydrogesterone Active ingredient (structurally similar to natural progesterone)
Lactose monohydrate Filler
Hypromellose Coating agent
Magnesium stearate Lubricant

(Gluten-free formulation)


3. MECHANISM OF ACTION

✔ Binds selectively to progesterone receptors
✔ Produces secretory endometrium → supports implantation
✔ Maintains pregnancy by preventing uterine contractions
✔ No thermogenic effect (basal body temperature unchanged)


4. DOSAGE & ADMINISTRATION

By Indication

Condition Dosage Regimen Duration
Endometriosis 10 mg 2-3x daily Days 5-25 of cycle
Dysmenorrhea 10 mg 2x daily Days 5-25 of cycle
Threatened Miscarriage 40 mg stat → 10 mg every 8h Until symptoms resolve +1 week
Luteal Phase Support 10 mg 2x daily From ovulation → 10-12 weeks gestation
HRT Combination 10 mg daily Last 12-14 days of estrogen cycle

Key Notes:

  • Take with food to reduce nausea

  • No need for dose tapering before discontinuation


5. INDICATIONS

✅ Menstrual disorders (dysmenorrhea, irregular cycles)
✅ Endometriosis
✅ Luteal phase defect (fertility treatments)
✅ Threatened/recurrent miscarriage
✅ HRT adjunct (endometrial protection)


6. STORAGE CONDITIONS

  • Temperature: Below 30°C

  • Humidity: Keep in original blister pack

  • Shelf Life: 3 years


7. KEY RECOMMENDATIONS

✔ For fertility patients:

  • Start after confirmed ovulation (avoid anovulatory cycles)

  • Combine with ultrasound monitoring

✔ For HRT:

  • Ensure adequate estrogen priming first

  • Withdraw bleeding expected after progestin phase

✔ Safety advantage:

  • No negative impact on lipids/carbohydrate metabolism


8. IMPORTANT SAFETY NOTES

Contraindications

❌ Severe hepatic impairment
❌ Known progesterone-sensitive tumors
❌ Undiagnosed vaginal bleeding

Adverse Effects

Common (≥1%) Rare (<0.1%)
Breakthrough bleeding Allergic reactions
Mild nausea Thrombotic events (very rare)
Breast tenderness

Pregnancy/Lactation

  • Pregnancy (Category not assigned): Safe for luteal support

  • Breastfeeding: Minimal milk transfer


9. COMPARISON WITH OTHER PROGESTINS

Parameter Dydrogesterone Medroxyprogesterone Micronized Progesterone
Androgenic Effects None Mild None
Sedation No No Yes
Fertility-Friendly Yes No Yes
Metabolic Impact Neutral Negative Neutral

10. PATIENT COUNSELING

✔ Take consistently at same times daily
✔ Report:

  • Heavy/prolonged bleeding

  • Severe abdominal pain

  • Visual disturbances (rare migraine precursor)
    ✔ Fertility patients:

  • Continue until placenta forms (∼10-12 weeks)

  • No abrupt discontinuation needed


CONCLUSION

Duphaston 10 mg offers targeted progesterone effects without androgenic/ metabolic side effects, making it ideal for:

  • Fertility support (no ovulation suppression)

  • Long-term endometrial protection in HRT

  • High-risk pregnancy management

Reviews

There are no reviews yet.

Be the first to review “DUPHASTON 10 MG”

Your email address will not be published. Required fields are marked *

  • Brand Name: Duphaston

  • Generic Name: Dydrogesterone

  • Therapeutic Class: Retroprogesterone (Synthetic Progestogen)

  • Form: 10 mg film-coated tablets

  • Key Feature:

    • No androgenic/estrogenic/glucocorticoid activity

    • Does not inhibit ovulation


2. COMPOSITION

Component Role
Dydrogesterone Active ingredient (structurally similar to natural progesterone)
Lactose monohydrate Filler
Hypromellose Coating agent
Magnesium stearate Lubricant

(Gluten-free formulation)


3. MECHANISM OF ACTION

✔ Binds selectively to progesterone receptors
✔ Produces secretory endometrium → supports implantation
✔ Maintains pregnancy by preventing uterine contractions
✔ No thermogenic effect (basal body temperature unchanged)


4. DOSAGE & ADMINISTRATION

By Indication

Condition Dosage Regimen Duration
Endometriosis 10 mg 2-3x daily Days 5-25 of cycle
Dysmenorrhea 10 mg 2x daily Days 5-25 of cycle
Threatened Miscarriage 40 mg stat → 10 mg every 8h Until symptoms resolve +1 week
Luteal Phase Support 10 mg 2x daily From ovulation → 10-12 weeks gestation
HRT Combination 10 mg daily Last 12-14 days of estrogen cycle

Key Notes:

  • Take with food to reduce nausea

  • No need for dose tapering before discontinuation


5. INDICATIONS

✅ Menstrual disorders (dysmenorrhea, irregular cycles)
✅ Endometriosis
✅ Luteal phase defect (fertility treatments)
✅ Threatened/recurrent miscarriage
✅ HRT adjunct (endometrial protection)


6. STORAGE CONDITIONS

  • Temperature: Below 30°C

  • Humidity: Keep in original blister pack

  • Shelf Life: 3 years


7. KEY RECOMMENDATIONS

✔ For fertility patients:

  • Start after confirmed ovulation (avoid anovulatory cycles)

  • Combine with ultrasound monitoring

✔ For HRT:

  • Ensure adequate estrogen priming first

  • Withdraw bleeding expected after progestin phase

✔ Safety advantage:

  • No negative impact on lipids/carbohydrate metabolism


8. IMPORTANT SAFETY NOTES

Contraindications

❌ Severe hepatic impairment
❌ Known progesterone-sensitive tumors
❌ Undiagnosed vaginal bleeding

Adverse Effects

Common (≥1%) Rare (<0.1%)
Breakthrough bleeding Allergic reactions
Mild nausea Thrombotic events (very rare)
Breast tenderness

Pregnancy/Lactation

  • Pregnancy (Category not assigned): Safe for luteal support

  • Breastfeeding: Minimal milk transfer


9. COMPARISON WITH OTHER PROGESTINS

Parameter Dydrogesterone Medroxyprogesterone Micronized Progesterone
Androgenic Effects None Mild None
Sedation No No Yes
Fertility-Friendly Yes No Yes
Metabolic Impact Neutral Negative Neutral

10. PATIENT COUNSELING

✔ Take consistently at same times daily
✔ Report:

  • Heavy/prolonged bleeding

  • Severe abdominal pain

  • Visual disturbances (rare migraine precursor)
    ✔ Fertility patients:

  • Continue until placenta forms (∼10-12 weeks)

  • No abrupt discontinuation needed


CONCLUSION

Duphaston 10 mg offers targeted progesterone effects without androgenic/ metabolic side effects, making it ideal for:

  • Fertility support (no ovulation suppression)

  • Long-term endometrial protection in HRT

  • High-risk pregnancy management

Reviews

There are no reviews yet.

Be the first to review “DUPHASTON 10 MG”

Your email address will not be published. Required fields are marked *

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Anteka Pharmacy primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Anteka Pharmacy. Our mission is to support, not replace, the doctor-patient relationship.
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