DUVADILAN

Women Health

Description
Shipping Options
Customer Reviews

DUVADILAN is a peripheral vasodilator and uterine relaxant containing Isoxsuprine HCl, primarily used for:

Peripheral vascular disorders
Threatened preterm labor (as a tocolytic)
Cerebral vascular insufficiency

Composition

Active Ingredient: Isoxsuprine Hydrochloride
Available Forms:
- Tablets: 10 mg, 20 mg
- Injection: 10 mg/2 mL ampoule
Excipients (tablet form):
- Lactose monohydrate
- Microcrystalline cellulose
- Magnesium stearate

Mechanism of Action

✔ β2-adrenergic agonist:

Relaxes vascular smooth muscle → peripheral vasodilation
Reduces uterine contractions → tocolytic effect

✔ Additional Effects:

Mild positive inotropic action on heart
Inhibition of platelet aggregation

Dosage & Administration

For Peripheral Vascular Disorders

Form	Dosage	Frequency
Oral	10-20 mg	3-4 times daily
IM	5-10 mg	2-3 times daily

For Threatened Preterm Labor

IV Infusion: 0.5-1 mg/min initially, then 0.1-0.2 mg/min maintenance
IM: 10 mg every 3-6 hours

Administration Notes

Oral: Take before meals for better absorption
Parenteral: Monitor maternal heart rate during tocolysis
Max Daily Dose: 120 mg (oral), 40 mg (parenteral)

Indications

✅ Peripheral vascular diseases:

Raynaud’s phenomenon
Arteriosclerosis obliterans
Diabetic vascular disease

✅ Obstetric use:

Threatened abortion
Premature labor

✅ Neurological use:

Cerebral vascular insufficiency
Vascular dementia

Storage & Stability

Tablets: Store below 30°C, protect from moisture
Injection: Store at room temperature (15-25°C)
Protect from light for both forms
Shelf life: Typically 3 years

Key Recommendations

✔ For vascular disorders:

Combine with physical therapy for best results
Monitor peripheral pulses and skin temperature

✔ For tocolysis:

Use with fetal monitoring
Limit duration to 48-72 hours
Combine with corticosteroids for fetal lung maturation

✔ General precautions:

Monitor blood pressure (may cause hypotension)
Assess for tachycardia (dose-dependent effect)

Important Safety Notes

⚠ Contraindications: ❌ Immediate postpartum period ❌ Severe coronary artery disease ❌ Recent arterial hemorrhage ❌ Hypersensitivity to sympathomimetics

⚠ Adverse Effects:

Common (≥5%)	Serious (<1%)
Tachycardia	Severe hypotension
Dizziness	Myocardial ischemia
Nausea	Pulmonary edema
Flushing	Uterine atony

⚠ Drug Interactions:

β-blockers: Antagonize effects
Other vasodilators: Enhanced hypotensive effect
MAO inhibitors: Potentiate action

Comparison with Similar Agents

Feature	DUVADILAN	Nifedipine	Ritodrine
Primary Use	Vascular/OB	OB	OB
Mechanism	β2-agonist	Ca²⁺ blocker	β2-agonist
Cardiac Effects	++	+	+++
Oral Bioavailability	50%	90%	30%

Patient Counseling

✔ For vascular patients:

Report palpitations or severe dizziness
Avoid sudden position changes
Importance of smoking cessation

✔ For obstetric use:

Recognize preterm labor signs
Understand medication purpose and limitations
Report chest pain or breathing difficulty

Conclusion

DUVADILAN remains a versatile vasodilator with unique obstetric applications, though its use in preterm labor has diminished with newer tocolytics. Requires careful cardiovascular monitoring in all indications.

DUVADILAN is a peripheral vasodilator and uterine relaxant containing Isoxsuprine HCl, primarily used for:

Peripheral vascular disorders
Threatened preterm labor (as a tocolytic)
Cerebral vascular insufficiency

Composition

Active Ingredient: Isoxsuprine Hydrochloride
Available Forms:
- Tablets: 10 mg, 20 mg
- Injection: 10 mg/2 mL ampoule
Excipients (tablet form):
- Lactose monohydrate
- Microcrystalline cellulose
- Magnesium stearate

Mechanism of Action

✔ β2-adrenergic agonist:

Relaxes vascular smooth muscle → peripheral vasodilation
Reduces uterine contractions → tocolytic effect

✔ Additional Effects:

Mild positive inotropic action on heart
Inhibition of platelet aggregation

Dosage & Administration

For Peripheral Vascular Disorders

Form	Dosage	Frequency
Oral	10-20 mg	3-4 times daily
IM	5-10 mg	2-3 times daily

For Threatened Preterm Labor

IV Infusion: 0.5-1 mg/min initially, then 0.1-0.2 mg/min maintenance
IM: 10 mg every 3-6 hours

Administration Notes

Oral: Take before meals for better absorption
Parenteral: Monitor maternal heart rate during tocolysis
Max Daily Dose: 120 mg (oral), 40 mg (parenteral)

Indications

✅ Peripheral vascular diseases:

Raynaud’s phenomenon
Arteriosclerosis obliterans
Diabetic vascular disease

✅ Obstetric use:

Threatened abortion
Premature labor

✅ Neurological use:

Cerebral vascular insufficiency
Vascular dementia

Storage & Stability

Tablets: Store below 30°C, protect from moisture
Injection: Store at room temperature (15-25°C)
Protect from light for both forms
Shelf life: Typically 3 years

Key Recommendations

✔ For vascular disorders:

Combine with physical therapy for best results
Monitor peripheral pulses and skin temperature

✔ For tocolysis:

Use with fetal monitoring
Limit duration to 48-72 hours
Combine with corticosteroids for fetal lung maturation

✔ General precautions:

Monitor blood pressure (may cause hypotension)
Assess for tachycardia (dose-dependent effect)

Important Safety Notes

⚠ Contraindications:
❌ Immediate postpartum period
❌ Severe coronary artery disease
❌ Recent arterial hemorrhage
❌ Hypersensitivity to sympathomimetics

⚠ Adverse Effects:

Common (≥5%)	Serious (<1%)
Tachycardia	Severe hypotension
Dizziness	Myocardial ischemia
Nausea	Pulmonary edema
Flushing	Uterine atony

⚠ Drug Interactions:

β-blockers: Antagonize effects
Other vasodilators: Enhanced hypotensive effect
MAO inhibitors: Potentiate action

Comparison with Similar Agents

Feature	DUVADILAN	Nifedipine	Ritodrine
Primary Use	Vascular/OB	OB	OB
Mechanism	β2-agonist	Ca²⁺ blocker	β2-agonist
Cardiac Effects	++	+	+++
Oral Bioavailability	50%	90%	30%

Patient Counseling

✔ For vascular patients:

Report palpitations or severe dizziness
Avoid sudden position changes
Importance of smoking cessation

✔ For obstetric use:

Recognize preterm labor signs
Understand medication purpose and limitations
Report chest pain or breathing difficulty

Conclusion

Shipping Options –

We offer a variety of shipping options, including Express Mail Service (EMS), USPS, DHL, FedEx, TNT, UPS, Aramex, Air Cargo, and sea freight.

Terms and Conditions –

Bulk Orders: You are responsible for any local import duties and taxes in your country.

For Patients: When ordering prescription medicines for personal use, or for a friend or relative, a valid medical practitioner’s script or prescription is required.

Return and Refund Policy: Due to the nature of our products, we cannot accept returns or exchanges once a purchase is made. However, in the event of non-delivery, you are eligible for either a 100% refund or a reshipment of your order.

Description
Reviews (0)

DUVADILAN is a peripheral vasodilator and uterine relaxant containing Isoxsuprine HCl, primarily used for:

Peripheral vascular disorders
Threatened preterm labor (as a tocolytic)
Cerebral vascular insufficiency

Composition

Active Ingredient: Isoxsuprine Hydrochloride
Available Forms:
- Tablets: 10 mg, 20 mg
- Injection: 10 mg/2 mL ampoule
Excipients (tablet form):
- Lactose monohydrate
- Microcrystalline cellulose
- Magnesium stearate

Mechanism of Action

✔ β2-adrenergic agonist:

Relaxes vascular smooth muscle → peripheral vasodilation
Reduces uterine contractions → tocolytic effect

✔ Additional Effects:

Mild positive inotropic action on heart
Inhibition of platelet aggregation

Dosage & Administration

For Peripheral Vascular Disorders

Form	Dosage	Frequency
Oral	10-20 mg	3-4 times daily
IM	5-10 mg	2-3 times daily

For Threatened Preterm Labor

IV Infusion: 0.5-1 mg/min initially, then 0.1-0.2 mg/min maintenance
IM: 10 mg every 3-6 hours

Administration Notes

Oral: Take before meals for better absorption
Parenteral: Monitor maternal heart rate during tocolysis
Max Daily Dose: 120 mg (oral), 40 mg (parenteral)

Indications

✅ Peripheral vascular diseases:

Raynaud’s phenomenon
Arteriosclerosis obliterans
Diabetic vascular disease

✅ Obstetric use:

Threatened abortion
Premature labor

✅ Neurological use:

Cerebral vascular insufficiency
Vascular dementia

Storage & Stability

Tablets: Store below 30°C, protect from moisture
Injection: Store at room temperature (15-25°C)
Protect from light for both forms
Shelf life: Typically 3 years

Key Recommendations

✔ For vascular disorders:

Combine with physical therapy for best results
Monitor peripheral pulses and skin temperature

✔ For tocolysis:

Use with fetal monitoring
Limit duration to 48-72 hours
Combine with corticosteroids for fetal lung maturation

✔ General precautions:

Monitor blood pressure (may cause hypotension)
Assess for tachycardia (dose-dependent effect)

Important Safety Notes

⚠ Contraindications:
❌ Immediate postpartum period
❌ Severe coronary artery disease
❌ Recent arterial hemorrhage
❌ Hypersensitivity to sympathomimetics

⚠ Adverse Effects:

Common (≥5%)	Serious (<1%)
Tachycardia	Severe hypotension
Dizziness	Myocardial ischemia
Nausea	Pulmonary edema
Flushing	Uterine atony

⚠ Drug Interactions:

β-blockers: Antagonize effects
Other vasodilators: Enhanced hypotensive effect
MAO inhibitors: Potentiate action

Comparison with Similar Agents

Feature	DUVADILAN	Nifedipine	Ritodrine
Primary Use	Vascular/OB	OB	OB
Mechanism	β2-agonist	Ca²⁺ blocker	β2-agonist
Cardiac Effects	++	+	+++
Oral Bioavailability	50%	90%	30%

Patient Counseling

✔ For vascular patients:

Report palpitations or severe dizziness
Avoid sudden position changes
Importance of smoking cessation

✔ For obstetric use:

Recognize preterm labor signs
Understand medication purpose and limitations
Report chest pain or breathing difficulty

Conclusion

Reviews

There are no reviews yet.

Be the first to review “DUVADILAN”

Description
Reviews (0)

DUVADILAN is a peripheral vasodilator and uterine relaxant containing Isoxsuprine HCl, primarily used for:

Peripheral vascular disorders
Threatened preterm labor (as a tocolytic)
Cerebral vascular insufficiency

Composition

Active Ingredient: Isoxsuprine Hydrochloride
Available Forms:
- Tablets: 10 mg, 20 mg
- Injection: 10 mg/2 mL ampoule
Excipients (tablet form):
- Lactose monohydrate
- Microcrystalline cellulose
- Magnesium stearate

Mechanism of Action

✔ β2-adrenergic agonist:

Relaxes vascular smooth muscle → peripheral vasodilation
Reduces uterine contractions → tocolytic effect

✔ Additional Effects:

Mild positive inotropic action on heart
Inhibition of platelet aggregation

Dosage & Administration

For Peripheral Vascular Disorders

Form	Dosage	Frequency
Oral	10-20 mg	3-4 times daily
IM	5-10 mg	2-3 times daily

For Threatened Preterm Labor

IV Infusion: 0.5-1 mg/min initially, then 0.1-0.2 mg/min maintenance
IM: 10 mg every 3-6 hours

Administration Notes

Oral: Take before meals for better absorption
Parenteral: Monitor maternal heart rate during tocolysis
Max Daily Dose: 120 mg (oral), 40 mg (parenteral)

Indications

✅ Peripheral vascular diseases:

Raynaud’s phenomenon
Arteriosclerosis obliterans
Diabetic vascular disease

✅ Obstetric use:

Threatened abortion
Premature labor

✅ Neurological use:

Cerebral vascular insufficiency
Vascular dementia

Storage & Stability

Tablets: Store below 30°C, protect from moisture
Injection: Store at room temperature (15-25°C)
Protect from light for both forms
Shelf life: Typically 3 years

Key Recommendations

✔ For vascular disorders:

Combine with physical therapy for best results
Monitor peripheral pulses and skin temperature

✔ For tocolysis:

Use with fetal monitoring
Limit duration to 48-72 hours
Combine with corticosteroids for fetal lung maturation

✔ General precautions:

Monitor blood pressure (may cause hypotension)
Assess for tachycardia (dose-dependent effect)

Important Safety Notes

⚠ Contraindications:
❌ Immediate postpartum period
❌ Severe coronary artery disease
❌ Recent arterial hemorrhage
❌ Hypersensitivity to sympathomimetics

⚠ Adverse Effects:

Common (≥5%)	Serious (<1%)
Tachycardia	Severe hypotension
Dizziness	Myocardial ischemia
Nausea	Pulmonary edema
Flushing	Uterine atony

⚠ Drug Interactions:

β-blockers: Antagonize effects
Other vasodilators: Enhanced hypotensive effect
MAO inhibitors: Potentiate action

Comparison with Similar Agents

Feature	DUVADILAN	Nifedipine	Ritodrine
Primary Use	Vascular/OB	OB	OB
Mechanism	β2-agonist	Ca²⁺ blocker	β2-agonist
Cardiac Effects	++	+	+++
Oral Bioavailability	50%	90%	30%

Patient Counseling

✔ For vascular patients:

Report palpitations or severe dizziness
Avoid sudden position changes
Importance of smoking cessation

✔ For obstetric use:

Recognize preterm labor signs
Understand medication purpose and limitations
Report chest pain or breathing difficulty

Conclusion

Reviews

There are no reviews yet.

Be the first to review “DUVADILAN”

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