PROGYNOVA

Women Health

Description
Shipping Options
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PROGYNOVA is an estrogen therapy medication containing Estradiol Valerate, a bioidentical estrogen used for menopausal symptom relief, hormone replacement therapy (HRT), and certain gynecological conditions.

Composition

Active Ingredient: Estradiol Valerate (1 mg or 2 mg tablets).
Inactive Ingredients: Lactose, maize starch, povidone, magnesium stearate.

Mechanism of Action

Estradiol Valerate converts to estradiol in the body, binding to estrogen receptors.
Relieves menopausal symptoms (hot flashes, vaginal dryness).
Prevents bone loss (osteoporosis) in postmenopausal women.
Regulates menstrual cycles in hypoestrogenic conditions.

Dosage & Administration

Common Indications & Dosing

Condition	Dosage	Duration
Menopausal symptoms	1–2 mg/day	Continuous or cyclic (21 days on, 7 days off)
Postmenopausal osteoporosis	0.5–1 mg/day	Long-term (with progesterone if uterus intact)
Hypoestrogenism	1–2 mg/day	Cyclic (3 weeks on, 1 week off)

Administration Notes

Take at the same time daily for consistent hormone levels.
With or without food (food may reduce nausea).
For women with a uterus, always combine with progesterone to prevent endometrial hyperplasia.

Indications

✅ Relief of menopausal symptoms (hot flashes, night sweats). ✅ Prevention of postmenopausal osteoporosis. ✅ Female hypogonadism (estrogen deficiency). ✅ Primary ovarian failure.

Storage & Stability

Store below 25°C, protect from moisture & light.
Keep in original packaging to prevent degradation.
Shelf life: Typically 2–3 years.

Key Recommendations

✔ Lowest effective dose for shortest duration (↑ risk of breast cancer with long-term use). ✔ Monitor blood pressure (estrogen can cause fluid retention). ✔ Annual breast exams & mammograms (due to estrogen-dependent cancer risk).

Important Safety Notes

⚠ Contraindications:

Breast/endometrial cancer (estrogen-sensitive tumors).
Active thromboembolism (DVT, stroke history).
Severe liver disease.

⚠ Pregnancy (Category X): Absolutely contraindicated (risk of fetal harm). ⚠ Side Effects:

Common: Breast tenderness, bloating, nausea.
Serious: Blood clots, stroke, gallbladder disease.

Comparison with Other Estrogens

Feature	PROGYNOVA (Estradiol Valerate)	Conjugated Estrogens (Premarin)	Transdermal Estradiol
Type	Bioidentical	Synthetic (horse-derived)	Bioidentical
Dosing	Oral (daily)	Oral (daily)	Patch/gel (weekly/daily)
Thrombosis Risk	Moderate	High	Lower (avoids first-pass liver)
Breast Cancer Risk	Dose-dependent	Higher risk	Possibly lower

Conclusion

PROGYNOVA is an effective oral estrogen for menopausal symptom relief & bone protection, but must be used cautiously due to thrombosis & cancer risks.

Composition

Active Ingredient: Estradiol Valerate (1 mg or 2 mg tablets).
Inactive Ingredients: Lactose, maize starch, povidone, magnesium stearate.

Mechanism of Action

Estradiol Valerate converts to estradiol in the body, binding to estrogen receptors.
Relieves menopausal symptoms (hot flashes, vaginal dryness).
Prevents bone loss (osteoporosis) in postmenopausal women.
Regulates menstrual cycles in hypoestrogenic conditions.

Dosage & Administration

Common Indications & Dosing

Condition	Dosage	Duration
Menopausal symptoms	1–2 mg/day	Continuous or cyclic (21 days on, 7 days off)
Postmenopausal osteoporosis	0.5–1 mg/day	Long-term (with progesterone if uterus intact)
Hypoestrogenism	1–2 mg/day	Cyclic (3 weeks on, 1 week off)

Administration Notes

Take at the same time daily for consistent hormone levels.
With or without food (food may reduce nausea).
For women with a uterus, always combine with progesterone to prevent endometrial hyperplasia.

Indications

✅ Relief of menopausal symptoms (hot flashes, night sweats).
✅ Prevention of postmenopausal osteoporosis.
✅ Female hypogonadism (estrogen deficiency).
✅ Primary ovarian failure.

Storage & Stability

Store below 25°C, protect from moisture & light.
Keep in original packaging to prevent degradation.
Shelf life: Typically 2–3 years.

Key Recommendations

✔ Lowest effective dose for shortest duration (↑ risk of breast cancer with long-term use).
✔ Monitor blood pressure (estrogen can cause fluid retention).
✔ Annual breast exams & mammograms (due to estrogen-dependent cancer risk).

Important Safety Notes

⚠ Contraindications:

Breast/endometrial cancer (estrogen-sensitive tumors).
Active thromboembolism (DVT, stroke history).
Severe liver disease.

⚠ Pregnancy (Category X): Absolutely contraindicated (risk of fetal harm).
⚠ Side Effects:

Common: Breast tenderness, bloating, nausea.
Serious: Blood clots, stroke, gallbladder disease.

Comparison with Other Estrogens

Feature	PROGYNOVA (Estradiol Valerate)	Conjugated Estrogens (Premarin)	Transdermal Estradiol
Type	Bioidentical	Synthetic (horse-derived)	Bioidentical
Dosing	Oral (daily)	Oral (daily)	Patch/gel (weekly/daily)
Thrombosis Risk	Moderate	High	Lower (avoids first-pass liver)
Breast Cancer Risk	Dose-dependent	Higher risk	Possibly lower

Conclusion

PROGYNOVA is an effective oral estrogen for menopausal symptom relief & bone protection, but must be used cautiously due to thrombosis & cancer risks.

Shipping Options –

We offer a variety of shipping options, including Express Mail Service (EMS), USPS, DHL, FedEx, TNT, UPS, Aramex, Air Cargo, and sea freight.

Terms and Conditions –

Bulk Orders: You are responsible for any local import duties and taxes in your country.

For Patients: When ordering prescription medicines for personal use, or for a friend or relative, a valid medical practitioner’s script or prescription is required.

Return and Refund Policy: Due to the nature of our products, we cannot accept returns or exchanges once a purchase is made. However, in the event of non-delivery, you are eligible for either a 100% refund or a reshipment of your order.

Description
Reviews (0)

Composition

Active Ingredient: Estradiol Valerate (1 mg or 2 mg tablets).
Inactive Ingredients: Lactose, maize starch, povidone, magnesium stearate.

Mechanism of Action

Estradiol Valerate converts to estradiol in the body, binding to estrogen receptors.
Relieves menopausal symptoms (hot flashes, vaginal dryness).
Prevents bone loss (osteoporosis) in postmenopausal women.
Regulates menstrual cycles in hypoestrogenic conditions.

Dosage & Administration

Common Indications & Dosing

Condition	Dosage	Duration
Menopausal symptoms	1–2 mg/day	Continuous or cyclic (21 days on, 7 days off)
Postmenopausal osteoporosis	0.5–1 mg/day	Long-term (with progesterone if uterus intact)
Hypoestrogenism	1–2 mg/day	Cyclic (3 weeks on, 1 week off)

Administration Notes

Take at the same time daily for consistent hormone levels.
With or without food (food may reduce nausea).
For women with a uterus, always combine with progesterone to prevent endometrial hyperplasia.

Indications

✅ Relief of menopausal symptoms (hot flashes, night sweats).
✅ Prevention of postmenopausal osteoporosis.
✅ Female hypogonadism (estrogen deficiency).
✅ Primary ovarian failure.

Storage & Stability

Store below 25°C, protect from moisture & light.
Keep in original packaging to prevent degradation.
Shelf life: Typically 2–3 years.

Key Recommendations

✔ Lowest effective dose for shortest duration (↑ risk of breast cancer with long-term use).
✔ Monitor blood pressure (estrogen can cause fluid retention).
✔ Annual breast exams & mammograms (due to estrogen-dependent cancer risk).

Important Safety Notes

⚠ Contraindications:

Breast/endometrial cancer (estrogen-sensitive tumors).
Active thromboembolism (DVT, stroke history).
Severe liver disease.

⚠ Pregnancy (Category X): Absolutely contraindicated (risk of fetal harm).
⚠ Side Effects:

Common: Breast tenderness, bloating, nausea.
Serious: Blood clots, stroke, gallbladder disease.

Comparison with Other Estrogens

Feature	PROGYNOVA (Estradiol Valerate)	Conjugated Estrogens (Premarin)	Transdermal Estradiol
Type	Bioidentical	Synthetic (horse-derived)	Bioidentical
Dosing	Oral (daily)	Oral (daily)	Patch/gel (weekly/daily)
Thrombosis Risk	Moderate	High	Lower (avoids first-pass liver)
Breast Cancer Risk	Dose-dependent	Higher risk	Possibly lower

Conclusion

PROGYNOVA is an effective oral estrogen for menopausal symptom relief & bone protection, but must be used cautiously due to thrombosis & cancer risks.

Reviews

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Description
Reviews (0)

Composition

Active Ingredient: Estradiol Valerate (1 mg or 2 mg tablets).
Inactive Ingredients: Lactose, maize starch, povidone, magnesium stearate.

Mechanism of Action

Estradiol Valerate converts to estradiol in the body, binding to estrogen receptors.
Relieves menopausal symptoms (hot flashes, vaginal dryness).
Prevents bone loss (osteoporosis) in postmenopausal women.
Regulates menstrual cycles in hypoestrogenic conditions.

Dosage & Administration

Common Indications & Dosing

Condition	Dosage	Duration
Menopausal symptoms	1–2 mg/day	Continuous or cyclic (21 days on, 7 days off)
Postmenopausal osteoporosis	0.5–1 mg/day	Long-term (with progesterone if uterus intact)
Hypoestrogenism	1–2 mg/day	Cyclic (3 weeks on, 1 week off)

Administration Notes

Take at the same time daily for consistent hormone levels.
With or without food (food may reduce nausea).
For women with a uterus, always combine with progesterone to prevent endometrial hyperplasia.

Indications

✅ Relief of menopausal symptoms (hot flashes, night sweats).
✅ Prevention of postmenopausal osteoporosis.
✅ Female hypogonadism (estrogen deficiency).
✅ Primary ovarian failure.

Storage & Stability

Store below 25°C, protect from moisture & light.
Keep in original packaging to prevent degradation.
Shelf life: Typically 2–3 years.

Key Recommendations

✔ Lowest effective dose for shortest duration (↑ risk of breast cancer with long-term use).
✔ Monitor blood pressure (estrogen can cause fluid retention).
✔ Annual breast exams & mammograms (due to estrogen-dependent cancer risk).

Important Safety Notes

⚠ Contraindications:

Breast/endometrial cancer (estrogen-sensitive tumors).
Active thromboembolism (DVT, stroke history).
Severe liver disease.

⚠ Pregnancy (Category X): Absolutely contraindicated (risk of fetal harm).
⚠ Side Effects:

Common: Breast tenderness, bloating, nausea.
Serious: Blood clots, stroke, gallbladder disease.

Comparison with Other Estrogens

Feature	PROGYNOVA (Estradiol Valerate)	Conjugated Estrogens (Premarin)	Transdermal Estradiol
Type	Bioidentical	Synthetic (horse-derived)	Bioidentical
Dosing	Oral (daily)	Oral (daily)	Patch/gel (weekly/daily)
Thrombosis Risk	Moderate	High	Lower (avoids first-pass liver)
Breast Cancer Risk	Dose-dependent	Higher risk	Possibly lower

Conclusion

PROGYNOVA is an effective oral estrogen for menopausal symptom relief & bone protection, but must be used cautiously due to thrombosis & cancer risks.

Reviews

There are no reviews yet.

Be the first to review “PROGYNOVA”

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