Adaly 40mg Adalimumab 40mg Injection is a medication used to treat:
- Rheumatoid Arthritis (RA): a chronic autoimmune disease that causes inflammation, stiffness, and pain in the joints
- Psoriatic Arthritis (PsA): a chronic autoimmune disease that causes inflammation, stiffness, and pain in the joints, as well as skin and nail symptoms
- Crohn’s Disease and Ulcerative Colitis: inflammatory bowel diseases that cause inflammation and damage in the digestive tract
Composition: Each vial of Adaly contains 40mg of Adalimumab (an active pharmaceutical ingredient), a tumor necrosis factor (TNF)-alpha inhibitor.
Mechanism of Action: Adalimumab works by:
- Binding to TNF-alpha, a protein that promotes inflammation and tissue damage
- Neutralizing the activity of TNF-alpha, which reduces inflammation and tissue damage
- Inhibiting the production of pro-inflammatory cytokines and chemokines
Dosage: The recommended dose of Adaly varies depending on the condition being treated:
- RA and PsA: 40mg every other week, injected subcutaneously (under the skin)
- Crohn’s Disease and Ulcerative Colitis: 40mg every other week, injected subcutaneously (under the skin)
Side Effects: Common side effects of Adaly include:
- Injection site reactions (e.g. redness, swelling, itching)
- Headache
- Fatigue
- Diarrhea
- Nausea or vomiting
- Rash or itching
Rare but serious side effects include:
- Serious infections (e.g. tuberculosis, bacterial sepsis)
- Cancer
- Autoimmune disorders (e.g. lupus-like syndrome)
- Neurological problems (e.g. multiple sclerosis-like syndrome)
Recommendation: Adaly is recommended for patients who have not responded to other treatments or who have had unacceptable side effects. Patients with active infections, cancer, or a history of tuberculosis should be closely monitored while taking Adaly.
Important Note:
- Adaly should be used under the guidance of a healthcare provider with experience in the treatment of RA, PsA, Crohn’s Disease, or Ulcerative Colitis.
- Patients should be advised to report any symptoms of hypersensitivity reactions, such as rash, itching, swelling, or difficulty breathing.
- Adaly may interact with other medications, such as antibiotics or immunosuppressants. Patients should inform their healthcare provider of all medications they are taking before starting Adaly therapy.
- Patients with a history of kidney disease or other medical conditions that may affect their ability to respond to treatment should be closely monitored while taking Adaly.
Special Precautions:
- Patients with active infections should be closely monitored while taking Adaly.
- Patients with a history of tuberculosis should be evaluated for active tuberculosis before starting Adaly therapy.
- Pregnant or breastfeeding women should consult their healthcare provider before taking Adaly.
- Patients with a history of cancer should be closely monitored while taking Adaly.
Indications:
- Rheumatoid Arthritis
- Psoriatic Arthritis
- Crohn’s Disease
- Ulcerative Colitis
Contraindications:
- Active tuberculosis
- Severe infections
- Cancer
- Pregnancy and breastfeeding (unless medically necessary)
Note: The above information is a general summary and is not intended to provide individualized advice or recommendations. It is always best to consult a healthcare provider for personalized guidance on the use of Adaly 40mg Adalimumab 40mg Injection.
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